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News and Events 2006

Prism Pharmaceuticals Raises $68 Million to Advance Acute Care Portfolio

KING OF PRUSSIA, Pa., September 18, 2006 - PRNewswire. Prism Pharmaceuticals, Inc., a privately-held, specialty pharmaceutical company committed to developing and commercializing acute care cardiovascular products, has secured up to $68 million in capital from Paul Capital Partners' Paul Royalty Fund II, L.P. ("Paul Capital") and existing investor Essex Woodlands Health Ventures Fund VI ("Essex")...more>

Prism and CyDex Pharmaceuticals, Inc. to Collaborate on Development of Captisol®-enabled Clopidogrel

June 6, 2006. Prism Pharmaceuticals and CyDex Pharmaceuticals, Inc. of Lenexa, Kansas, entered into a Joint Due Dligence and Collaborative Development and Discussion Agreement for novel formulations of clopidogrel employing CyDex's proprietary and patented technology identified by the trademark Captisol. CyDex will take the lead on non-clinical and intellectual property management. Prism will lead the regulatory development and commercialization activities. Products from this collaboration are not expected to enter the market prior to the expiration of prevailing patents for PLAVIX® (clopidogrel bisulfate). Terms were not disclosed. For further information on CyDex and Captisol, go to www.cydexpharma.com.

HollisterStier Contract Manufacturing Signs Agreement with Prism Pharmaceuticals, Inc.

April 4, 2006. HollisterStier Contract Manufacturing, a leading manufacturer of high quality sterile injectable products for the global pharmaceutical and biopharmaceutical markets, has signed a Letter of Intent with Prism Pharmaceuticals, Inc. to develop a process for compounding and fill/finishing Prism’s PM101, an acute care cardiovascular drug. HollisterStier is producing PM101 registration material for clinical trials and is supporting Prism Pharmaceuticals filing of a New Drug Application (NDA). PM101 will be filled into vials and syringes...more>

Prism licenses Captisol®-enabled Amiodarone IV from CyDex Pharmaceuticals, Inc.

January 4, 2006. Prism Pharmaceuticials and CyDex Pharmaceuticals, Inc., of Lenexa, Kansas, executed a licensing agreement granting worldwide rights for the development and commercialization for Captisol-enabled Amiodarone IV. CyDex's proprietary solubilizing technology enabled the formulation of injectible amiodarone without its original cosolvents, polysorbate 80 and benzyl alcohol. Terms were not disclosed. For further information on CyDex and Captisol, go to www.cydexpharma.com.


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